Most side-effects listed for statins are not caused by the drugs, a major review has found. Researchers analysed 19 trials involving 124,000 people and published the results in The Lancet. Apart from muscle pain, diabetes risk, and four minor effects, evidence did not support 62 listed side-effects, including memory loss, depression, and sleep problems. The review showed statins greatly reduce heart attacks, strokes, and cardiovascular deaths, while proven risks remain small. Lead author Christina Reith said benefits clearly outweigh harms for most patients. Senior researchers called for updated drug labels to reflect the evidence and support informed decisions.
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